Community AnswerAnswered by Dr. Emily Carter, MDAnswered: 11/18/2024Low A1C levels can be caused by several factors, including: Frequent Low Blood Sugar (Hypoglycemia): If you frequently experience low blood sugar, it can result in a lower A1C. Anemia or Blood Disorders: Conditions like iron-deficiency anemia or hemolytic anemia can affect A1C results. Recent Blood Loss or Transfusion: Blood loss or receiving a blood transfusion can temporarily lower A1C levels. Liver or Kidney Disease: These conditions can impact red blood cell turnover, affecting A1C. Medications: Certain medications, such as those used to treat HIV or iron supplements, can influence A1C levels. If you have a low A1C, it's important to consult with your healthcare provider to determine the underlying cause and appropriate management.