Community Answer

Answered by Dr. Emily Smith, MD

Yes, the A1C test can sometimes provide inaccurate results due to various factors. Here are some conditions and situations that may affect the accuracy of the A1C test:

  • Anemia: Severe anemia, especially iron-deficiency anemia, can lead to falsely high or low A1C results.
  • Kidney or Liver Disease: These conditions can interfere with the test's accuracy.
  • Blood Disorders: Conditions like sickle cell anemia or thalassemia can cause misleading A1C results.
  • Medications: Certain drugs, including opioids and some HIV medications, can affect A1C levels.
  • Pregnancy: Hormonal changes during pregnancy can impact A1C readings.
  • Blood Loss or Transfusions: Recent blood loss or transfusions can alter A1C results.

If you suspect your A1C result is inaccurate, consult your healthcare provider. They may recommend alternative tests or repeat the A1C test under different conditions.

Last updated: 1/16/2025